The actor, 53, was shooting a stunt for the third instalment of his movie franchise John Wick in Brooklyn.
The sequence involved Keanu racing through the streets as he tried to catch his high-speed assailant.
The scenes were shot several times in the early hours of Monday morning.
John Wick 3: Parabellum – in which Keanu reprises the lead role – is due to hit screens in May next year.
Earlier this year, Keanu revealed he regretted not sleeping with more adoring female fans.
The Canadian actor said that after starring in River's Edge he would have knickers thrown at him – but did not often act on it.
The Matrix star said: "I probably should have taken more advantage but I didn’t.
"You know, I was a little self conscious about that. I mean I’m not saying it didn’t happen sometimes."
He also admitted in the Esquire interview that he very nearly died in a motorbike accident.
The star said he took a hairpin bend too fast and lay on the pavement for half an hour thinking he was going to die.
The accident left a thick scar up his abdomen and necessitated the removal of his spleen.
He also had surgery for fake teeth, veneers and some broken ribs.
Reeves added: "You know, it's weird. After the accidents the adrenaline kicks in, so it’s not really painful. Maybe the broken ribs part. That was pretty uncomfortable."
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