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Rosie O’Donnell regrets making fun of Anne Heche on stage following the actress’ quirky interview with Barbara Walters back in 2001.

The comedian, 60, took to TikTok on Sunday to address the fiery car crash that’s left Heche, 53, in “critical condition” and fighting for her life.

“I can’t stop thinking about this Anne Heche accident and how horrifying the whole thing is and feeling bad that I made fun of her when she was talking to Barbara Walters about having a relationship with space aliens,” O’Donnell said in the TikTok video.

“If we have an honest discussion about drunk driving, we find out just how prevalent it is and that’s terrifying, isn’t it?” she added, implying that Heche may have been under the influence, which cops suspect.

“I wonder if she’s OK. I think it’s a miracle that she didn’t kill anyone … and I hope she survives. But wow, what a tragic tale. That car was on fire for a long time, they say.”

The “View” alum then urged her followers to seek help “if [they] are struggling” with alcoholism.

“Try it before it’s too late,” she advised. “Try it before you’re at your lowest.”

Back in 2001, during a “20/20” interview with Walters, Heche alleged she created a “fantasy world” and a second personality called Celestia after she was sexually molested by her father, Donald, when she was younger.

“I’m not crazy. But it’s a crazy life. I was raised in a crazy family and it took 31 years to get the crazy out of me,” Heche told Walters at the time.

“I had a fantasy world that I escaped to. I called my other personality Celestia,” she noted, claiming that this other persona had supernatural powers. “I believed I was from that world. I believed I was from another planet. I think I was insane.”

O’Donnell later mocked Heche for the interview at an Ovarian Cancer Research benefit at Carolines Comedy Club in Times Square in 2002, according to USA Today.

“What the hell kind of train wreck was that?” the comedian reportedly asked the crowd, before poking fun at Heche’s sexuality and her former relationship with Ellen DeGeneres.

“She couldn’t just say, ‘I was a lesbian for two years, it didn’t work out for me?’”

As Page Six previously reported, Heche has been fighting for her life since last Friday, when she was left severely burned after an accident left her car “engulfed” in flames.

“Shortly after the accident, Anne Heche became unconscious, slipping into a coma,” her spokesperson told Page Six on Monday. “She has a significant pulmonary injury requiring mechanical ventilation and burns that require surgical intervention.”

Earlier that day, Page Six confirmed that the Los Angeles Police Department obtained a warrant to test the actress’ blood as they believe she may have been under the influence of drugs and/or alcohol when she crashed her car into an LA home.

“If found intoxicated, [Heche] could be charged with misdemeanor DUI hit and run. No arrests have been made so far,” the statement read.

According to eyewitnesses, Heche first crashed into the garage of an apartment complex but sped off before residents could help her.

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