Only Keanu Reeves and Carrie-Ann Moss have returned for the fourth movie Matrix: Resurrections, which opens in cinemas on December 22.
Leading the brave resistance against the machines as Morpheus in the 1999 sci-fi classic, Laurence Fishburne was surprised not to receive a call to come back for the reboot.
But it was no shock that Marcus Chong – who played his shipmate Tank – didn’t receive an invite after being written out of the sequels over a pay dispute.
Another star overcame drugs abuse, one almost died and a fan favourite sadly passed away while making the second film.
Here we look at where the Matrix rebels are now.
The man who played the Judas figure in The Matrix got hooked on sex and prescription drugs.
Joe Pantoliano 70, has written two books about his struggles with depression after getting clean and founded an organisation called No Kidding, Me Too! to help others.
The New Jersey-born actor, who also starred in the 1983 Tom Cruise hit Risky Business, appeared in Bad Boys For Life with Will Smith last year.
He said: “As a young man, I lied my way out of all kinds of situations. So acting seemed a natural segue into a future where you could make a living out of lying.”