Spain has confirmed the country's first case of coronavirus after a man was diagnosed with the flu-like virus.
The patient is one of five German nationals who have been held in isolation in La Gomera, a rural island in the Canaries, according to the country's National Centre for Microbiology.
It comes after British Airways and Spain’s Iberia have both suspended all flights to China.
The total number of deaths from a coronavirus epidemic in China had reached 259 by the end of Friday, an increase of 46, state broadcaster CCTV said, citing numbers from the country's National Health Commission.
There were 2,102 new confirmed infections in China during the day, bringing the cumulative total to 11,791.
The local health commission of Hubei Province, the epicenter of the epidemic, earlier on Saturday reported 45 new deaths from the outbreak on Friday, bringing the total to 259.
The province remains under virtual quarantine, with roads sealed off and public transport shut down, but small numbers of travellers continue to breach the lockdown.
The World Health Organization declared the outbreak a public health emergency of international concern on Thursday.
Cities across China have continued to implement special measures aimed at curbing the spread of the pathogen.
Tianjin, a city in northern China with around 15 million people, said all schools and businesses would be suspended until further notice.
Amid fears that the virus could spread further overseas, the United States announced measures to restrict entry to foreign nationals who have recently been in China.
All three major U.S. airlines announced the cancellation of flights to mainland China on Friday.
Public Health England confirmed the virus is now in Britain after two members of the same family tested positive for the virus.
It is believed the patients are tourists and it is understood they had been staying at a hotel in Yorkshire.
The two patients are in a high consequence infectious disease unit, said Professor Chris Whitty, chief medical officer for England.
Meanwhile, Brits who have been flown back from Wuhan will spend 14 days in quarantine at a special facility in Arrowe Park Hospital.
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